Gonadotropin-Releasing Hormone (GnRH) Agonists for Fertility Preservation: Is POEMS the Final Verse?
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چکیده
منابع مشابه
Gonadotropin-Releasing Hormone (GnRH) Analogs or Active Immunization Against GnRH To Control Fertility in Wildlife
The administration of analogs, both agonists and for nonlethal population control of wildlife species. antagonists, of GnRH and immunization agalnst GnRH have Relatively little research has been done in this area. This been investigated for their ability to control reproductive chapter reviews relevant studies with domestic species and function in domestic species. These methods can be used dis...
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Gonadotropin-releasing hormone (GnRH) regulates reproduction. The human GnRH receptor lacks a cytoplasmic carboxy-terminal tail but has amino acid sequence motifs characteristic of rhodopsin-like, class A, G protein-coupled receptors (GPCRs). This review will consider how recent descriptions of X-ray crystallographic structures of GPCRs in inactive and active conformations may contribute to und...
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The gonadotropin-releasing hormone (GnRH) receptor in catfish differs from its mammalian counterparts in showing a very low affinity for the hypothalamic GnRH form [i.e. catfish GnRH (cfGnRH)] and a very high affinity for the highly conserved mesencephalic GnRH, chicken GnRH-II (cGnRH-II). In the present study we investigated the molecular interactions between ligand and receptor involved in de...
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Gonadotropin-releasing hormone (GnRH) acts via G-protein-coupled receptors on gonadotrophs to stimulate synthesis and secretion of luteinizing hormone and follicle-stimulating hormone. It is secreted in pulses, and its effects depend on pulse frequency, but decoding mechanisms are unknown. Here we have used an extracellular signal regulated kinase-green fluorescent protein (ERK2-GFP) reporter t...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2018
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djy188